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REVIEW ARTICLE 2016 September 15
Effects of early menarche on physical and psychosocial health problems in adolescent girls and adult women
The menarcheal age of Korean women has been rapidly decreasing for the last 50 years, and the average menarcheal age of women born in the 1990s is approaching 12.6 years. In addition, interest in early puberty has been increasing recently owing to the rapid increase in precociou...
ORIGINAL ARTICLE 2016 September 15
Risk factors of delayed diagnosis of acute appendicitis in children: for early detection of acute appendicitis
Purpose: This study examined the risk factors of a delayed diagnosis of acute appendicitis in children undergoing an appendectomy. Methods: This retrospective study involved children aged below 18 years, who underwent an appendectomy. After dividing them into a delayed diagnosi...
CASE REPORT 2016 September 15
Painful legs and moving toes syndrome in a 16-year-old girl
Painful legs and moving toes (PLMT) syndrome is characterized by spontaneous movements of the digits and pain in one or both lower extremities. Of the reported cases, a majority of the patients was female, and the mean age of onset was 58 years. Only one pediatric case has been ...
ORIGINAL ARTICLE 2016 September 15
Metformin displays in vitro and in vivo antitumor effect against osteosarcoma
Purpose: Patients with unresectable, relapsed, or refractory osteosarcoma need a novel therapeutic agent. Metformin is a biguanide derivative used in the treatment of type II diabetes, and is recently gaining attention in cancer research. Methods: We evaluated the effect of met...
ORIGINAL ARTICLE 2016 September 15
Clinical significance of serum alanine aminotransferase and lifestyle intervention in children with nonalcoholic fatty liver disease
Purpose: This study aimed to investigate the clinical significance of serum alanine aminotransferase (ALT) levels in children with nonalcoholic fatty liver disease (NAFLD) and the effect of lifestyle intervention on NAFLD. Methods: The clinical data of 86 children diagnosed wit...
REVIEW ARTICLE 2016 September 15
Apparent life-threatening event in infancy
An apparent life-threatening event (ALTE) is defined as the combination of clinical presentations such as apnea, marked change in skin and muscle tone, gagging, or choking. It is a frightening event, and it predominantly occurs during infancy at a mean age of 1–3 months. T...
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eISSN : 2092-7258
pISSN : 1738-1061
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Volume 59(9); Sep 2016
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