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Korean J Pediatr 1995 February;98(2) :264-270.
A Case of Intractable Ulcerating Enterocolitis" of Infant"
Ju Young Jeong (Jeong JY)3, Jeong Kee Seo (Seo JK)3, Kwi Won Park (Park KW)2, Je Geun Chi (Chi JG)1
1Department of Pathology, College of Medicine, Seoul University, Seoul, Korea
2Department of Surgery of Pediatrics, College of Medicine, Seoul University, Seoul, Korea
3Department of Pediatrics, College of Medicine, Seoul University, Seoul, Korea
Copyright © 1995 by The Korean Pediatric Society
Intractable ulcerating enterocolitis of infancy is uncommon, inhereditary disease characterized by ulcerating stomatitis, severe perianal disease, affecting the whole gastrointestinal tract, mainly colon with flask shaped large ulcer. It was first described by Sanderson et al in 5 cases of infant with intractable diarrhea having above clinical manifestation. It should be differentiated with Crohn's disease and Behcet's disease. We experienced a case of intractable ulcerating enterocolitis in an infant. A 17 month old patient was admitted because of intractable diarrhea since 2 months of age. Radilogical and endoscopic examination revealed chronic ulcerative inflammation with pseudopolyps involving ileum and entire colon. Ileocolectomy was performed because of its unresponsiveness to medical theraphy. The histology of resected specimen showed large flask shaped ulcer with underlying edge in the colon, terminal ileum. No evidence of granuloma suggesting Crohn's disease or vasculitis suggesting Behcet's colitis were noted. We report this case as an example of "intractable ulcerating enterocolitis"(Sanderson et al).
Keywords: Intractable diarrhea | Ulcerating enterocolitis
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