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ORIGINAL ARTICLE
Korean J Pediatr 2003 September;46(9) :893-897.
Efficacy of Antiepileptic Drug on the Benign Childhood Epilepsy with Centro-Temporal Spikes
Mee Hye Oh (Oh MH), Soo Young Kim (Kim SY), Won Hee Seo (Seo WH), Dae Hun Pee (Pee DH), Byung Min Choi (Choi BM), Baik-Lin Eun (Eun BL)
Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea
Corresponding Author: Baik-Lin Eun ,Email: bleun@chol.com
Copyright © 2003 by The Korean Pediatric Society
ABSTRACT
Purpose : Benign childhood epilepsy with centrotemporal spikes(BECT) is characterized by an excellent prognosis. Therefore, the necessity for the use of antiepileptic drugs is controversial. The object of this study is to know about the long-term follow-up of BECT, comparing daily treatment with antiepileptic drug(AED) versus no medication. Methods : We retrospectively studied 56 cases of BECTs, examined at Pediatric Neurology Clinic, Korea University Medical Center as reference study time, August 2002. Thirty-eight patients didn't have mediation(group I), while eighteen patients received one or two AED(group II). We evaluated demographics, clinical manifestations at diagnosis, EEG findings and clinical courses in groups I & II. Results : There was no significant differences of sex, age, seizure frequency, seizure type, seizure onset time, family history and EEG findings between group I & II. The reasons to start AED were : parents' anxiety(three cases), frequent seizure(12 cases) and daytime seizure(three cases). There was no evolution of status epilepticus and no difficulty in school performance. Conclusion : AED treatment was of no advantage and long-term prognosis was good regardless of treatment strategy. So it is advisable not to choose AED as the first line of therapy, provided that the patient himself/herself or the family understands the benign nature of BECT.
Keywords: Antiepileptic drug | Benign childhood epilepsy with centro-temporal spikes
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