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Korean J Pediatr 2010 April;53(4) :603-606.
A case of paraneoplastic limbic encephalitis due to ovarian mature teratoma
Seong Heon Kim (Kim SH), hye Young Kim (Kim hY), Young Tak Im (Im YT), Sang Ook Nam (Nam SO), Young Mi Kim (Kim YM)
Department of Pediatrics, Pusan National University Hospital, Pusan National University College of Medicine, Busan, Korea
Corresponding Author: Young Mi Kim ,Email:
Copyright © 2010 by The Korean Pediatric Society
Paraneoplastic limbic encephalitis, a remote effect of cancer without nervous system metastasis, is rare, especially in childhood. Here, we report a case of paraneoplastic limbic encephalitis associated with an ovarian mature teratoma in an adolescent girl. The 15-year-old girl developed neuropsychiatric symptoms, memory loss, seizures, and unconsciousness. Cerebrospinal fluid analysis and brain magnetic resonance imaging (MRI) findings were normal, while single photon emission computed tomography imaging showed hypoperfusion in both temporal lobes. Ultrasound and MRI of the abdomen revealed a left ovarian cystic mass. The patient experienced a significant recovery of cognitive function after surgical resection of the tumor, which was pathologically identified as a mature ovarian teratoma, and treatment with intravenous immunoglobulin.
Keywords: Paraneoplastic limbic encephalitis | Teratoma | Adolescent
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