Advanced Search
ORIGINAL ARTICLE
Korean J Pediatr 2010 September;53(9) :840-844.
doi:https://doi.org/10.3345/kjp.2010.53.9.840
Microalbuminuria in children with urinary tract infection
Byung Ok Kwak (Kwak BO), Sochung Chung (Chung Sc), Kyo Sun Kim (Kim KS)
Department of Pediatrics, School of Medicine, Konkuk University, Seoul, Korea
Corresponding Author: Kyo Sun Kim ,Email: kimkyo@kuh.ac.kr
Copyright © 2010 by The Korean Pediatric Society
ABSTRACT
Purpose : Microalbuminuria is defined as increased urinary albumin excretion (30-300 mg/day) or microalbumin/creatinine ratio (30-300 mg/g) in a spot urine sample. Although microalbuminuria is a predictor of clinical nephropathy and cardiomyopathy, few studies have investigated microalbuminuria in children with urinary tract infection (UTI). Therefore, we compared the spot urine microalbumin/creatinine ratio in pediatric UTI patients with that of control subjects. Methods : We investigated the correlation between the ratio in children with UTI and age, height, weight, blood pressure, glomerular filtration rate (GFR), hematuria, vesicoureteral reflux, renal parenchymal defect, and renal scar, and its predictability for UTI complications. Results : We studied 66 patients (42 boys, 24 girls) and 52 healthy children (24 boys, 28 girls). The mean microalbumin/creatinine ratio in UTI patients was statistically significantly increased compared to the control group (340.04321.36 mg/g vs. 225.68154.61 mg/g, P=0.0141). The mean value of spot urine microalbumin/creatinine ratio (384.70342.22 mg/g vs. 264.92158.13 mg/g, P=0.0341) in 1-23 months age patient group showed statistically significant increase compared to control group. Microalbumin/creatinine ratio showed negative correlation to age (r=-0.29, P=0.0167), body surface area (BSA) (r=-0.29, P=0.0173) and GFR (r=-0.26, P=0.0343). The presence of hematuria (P=0.0169) was found to be correlated. Conclusion : The spot urine microalbumin/creatinine ratio in children with UTI was significantly greater than that in normal children, and it was positively correlated with GFR. This ratio is a potential prescreening and prognostic marker in UTI patients. Further studies are required to validate the predictability of microalbuminuria in pediatric UTI patients.
Keywords: Microalbuminuria | Child | Urinary tract infection
TOOLS
PDF Links  PDF Links
Full text via DOI  Full text via DOI
  via Pubmed
Full text via PMC  Full text via PMC
via Pubreader  via PubReader
Download Citation  Download Citation
Supplementary Material  Supplementary Material
  E-Mail
Share:      
METRICS
1,325
View
8
Download
Usefulness of neutrophil-lymphocyte ratio in young children with febrile urinary tract infection  2016 March;59(3)
Molecular typing of uropathogenic Escherichia coli isolated from Korean children with urinary tract infection  2015 January;58(1)
Renal scar formation after urinary tract infection in children  2012 October;55(10)
Regional differences in phylogenetic group of Escherichia coli strains isolated from children with urinary tract infection in Korea  2012 November;55(11)
Macroamylasemia in a 4-year-old girl with abdominal pain  2009 November;52(11)
Register for e-submission
Register here to access the e-submission system of Korean J Pediatr for authors and reviewers.
Manuscript Submission
To submit a manuscript, please visit the Korean J Pediatr e-submission management system at http://submit.kjp.or.kr, read the Instructions for Authors, and log into the Korean J Pediatr e-submission system. For assistance with manuscript submission, please contact: kjpped@gmail.com.
Free archive
Anyone may access any past or current articles without logging in.
Korean Pediatric Society Office
#1606, Seocho World Officetel, 19 Seoun-ro, Seocho-gu, Seoul 137-070, Korea
TEL : +82-2-3473-7305    FAX : +82-2-3473-7307   E-mail: kjpped@gmail.com
BrowseCurrent IssueFor Authors and ReviewersAbout
Copyright© The Korean Pediatric Society. All right reserved.