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Korean J Pediatr 2010 September;53(9) :859-862.
Transient splenial lesion of the corpus callosum in a case of benign convulsion associated with rotaviral gastroenteritis
Yoon Young Jang (Jang YY), Kye Hyang Lee (Lee KH)
Department of Pediatrics, College of Medicine, Daegu Catholic University, Daegu, Korea
Corresponding Author: Kye Hyang Lee ,Email:
Copyright © 2010 by The Korean Pediatric Society
Transient magnetic resonance (MR) signal changes in the splenium of the corpus callosum (SCC) arise from many different conditions, including encephalopathy or encephalitis caused by infection, seizures, metabolic derangements, and asphyxia. Few case reports exist on reversible SCC lesions associated with rotavirus infection. A benign convulsion with mild gastroenteritis (CwG) is frequently associated with rotaviral infections. This entity is characterized by normal laboratory findings, electroencephalogram, neuroimaging, and good prognosis. We report a case of a 2.5-year-old Korean girl with rotavirus-associated CwG demonstrating a reversible SCC lesion on diffusion-weighted MR images. She developed 2 episodes of brief generalized tonic-clonic seizure with mild acute gastroenteritis without any other neurologic abnormality. Stool test for rotavirus antigen was positive. Brain MRI done on the day of admission showed a linear high signal intensity and decreased apparent diffusion coefficient values on the SCC. The lesion completely disappeared on follow-up MRI 6 days later. The patient fully recovered without any sequelae.
Keywords: Corpus callosum | Magnetic resonance imaging | Diffusion | Rotavirus infection | Seizures | Child
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Supplementary Material  Supplementary Material
Clinical features of acute noroviral gastroenteritis in children : comparison with rotaviral gastroenteritis  2009 April;52(4)
Clinical Features of Benign Infantile Convulsions with Gastroenteritis  2005 July;48(7)
A Clinical Study on Benign Convulsions with Mild Gastroenteritis  2004 December;47(12)
Clinical Study of Benign Convulsion with Acute Gastroenteritis  2004 August;47(8)
A Clinical Study of Neurologic Abnormalities Associated with Rotavirus Gastroenteritis  2004 July;47(7)
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