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Korean J Pediatr 2010 October;53(10) :913-916.
A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency
Won Seok Lee (Lee WS), Young Sil Park (Park YS)
Department of Pediatrics, Kyung Hee University School of Medicine, Seoul, Korea
Corresponding Author: Young Sil Park ,Email:
Copyright © 2010 by The Korean Pediatric Society
Congenital factor VII deficiency is a rare autosomal-recessive bleeding disorder. Bleeding manifestations and clinical findings vary widely, ranging from asymptomatic subjects to patients with hemorrhages that may cause significant handicaps. Treatment has traditionally involved factor VII(FVII) replacement therapy using fresh frozen plasma, prothrombin complex concentrates or plasma-derived FVII concentrates. Recombinant activated FVII (NovoSevenc) is currently considered the first-line treatment for replacement therapy of FVII deficiency. Here we present a case of severe intracerebral and intraventricular hemorrhage in a neonate with congenital FVII deficiency.
Keywords: Congenital factor VII deficiency | Intracranial hemorrhage | Neonate
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