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Korean J Pediatr 2011 February;54(2) :64-68.
Reference values for respiratory system impedance using impulse oscillometry in healthy preschool children
Jye Hae Park (Park JH)1, Jung Won Yoon (Yoon JW)1, Youn Ho Shin (Shin YH)1, Hye Mi Jee (Jee HM)1, Young Sun Wee (Wee YS)1, Sun Jung Chang (Chang SJ)1, Jung Hwa Sim (Sim JH)1, Hye Yung Yum (Yum HY)2, Man Yong Han (Han MY)1
1Department of Pediatrics, CHA Bundang Medical Center, CHA University, Seongnam, Gyeonggi-do,Korea
2Atopy Clinic, Seoul Medical Center, Seoul, Korea
Corresponding Author: Man Yong Han ,Tel: +82.31-780-6262, Fax: +81.31-780-5239, Email:
Copyright © 2011 by The Korean Pediatric Society
Purpose : The normal values for lung resistance and lung capacity of children, as determined by impulse oscillometry (IOS), are different for children of different ethnicities. However, reference values there is no available reference value for Korean preschool children have yet to be determined. The aim of the present study was to determine the normal ranges of IOS parameters in Korean preschool children. Methods : A total of 133 healthy Korean preschool children were selected from 639 children (aged 3 to 6 years) who attended kindergarten in Seongnam, Gyeonggi province, Korea. Healthy children were defined according to the European Respiratory Society (ERS) criteria. All subjects underwent lung function tests using IOS. The relationships between IOS value (respiratory resistance (Rrs) and reactance (Xrs) at 5 and 10 Hz and resonance frequency (RF)) and age, height, and weight were analyzed by simple linear and multiple linear regression analyses. Results : The IOS success rate was 89.5%, yielding data on 119 children. Linear regression identified height as the best predictor of Rrs and Xrs. Using stepwise multiple linear regressions based on age, height, and weight, we determined regression equations and coefficients of determination (R2) for boys (Rrs5=1.934– 0.009Height, R2=12.1%; Xrs5=0.774+0.006Height–0.002Age, R2=20.2% and for girls (Rrs5=2.201–0.012Height, R2=18.2%; Xrs5=-0.674+0.004Height, R2=10.5%). Conclusion : This study provides reference values for IOS measurements of normal Korean preschool children. These provide a basis for the diagnosis and monitoring of preschool children with a variety of respiratory diseases.
Keywords: Impulse oscillation system | Reference values | Airway resistance | Preschool children
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Reference values for respiratory system impedance using impulse oscillometry in school-aged children in Korea  2007 September;50(9)
Age Related Reference Ranges for Lymphocyte Subsets in Healthy Korean Children  1996 February;39(2)
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