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Korean J Pediatr 2011 March;54(3) :123-127.
Mycoplasma pneumoniae infection in patients with Kawasaki disease
Mi Na Lee (Lee MN)1, Jie Hae Cha (Cha JH)1, Hye Mi Ahn (Ahn HM)1, Jeong Hyun Yoo (Yoo JH)2, Hae Soon Kim (Kim HS)1, Sejung Sohn (Sohn Sj)1, Young Mi Hong (Hong YM)1
1Departments of Pediatrics, and Radiology, Ewha Womans University, School of Medicine, Seoul, Korea
2Departments of Pediatrics, and Radiology, Ewha Womans University, School of Medicine, Seoul, Korea
Corresponding Author: Young Mi Hong ,Tel: +82.2-2650-2841, Fax: +82.2-2653-3718, Email:
Copyright © 2011 by The Korean Pediatric Society
Purpose : Kawasaki disease (KD) is the main cause of acquired heart disease in children. In addition to cardiovascular involvement, many complications have been recognized in KD. However, respiratory complications have been rarely reported. We investigated the differences in clinical characteristics, laboratory findings, radiography findings, and echocardiography findings of Mycoplasma pneumoniae infection and other types of pneumonia in KD patients. Methods : Among 358 patients with KD, 54 developed concurrent pneumonia. Among the 54 patients, 12 (22.2%) with high titers of anti-M. pneumoniae antibody (AMA) (>1:640) were grouped in the M. pneumoniae group and 42 were included in the control group. Serum AMA was measured in each patient. Clinical laboratory findings and total duration of fever were analyzed. Results : The duration of fever, serum hemoglobin, white blood cell count, platelet count, erythrocyte sedimentation rate, C-reactive protein level, albumin level, and the incidence of coronary arterial lesions showed no statistical difference in the 2 groups. Neutrophil count was significantly higher in the M. pneumoniae group than in the control group. Among various radiography findings observed in pneumonia, consolidation and pleural effusion were more frequent in the M. pneumoniae group than in the control group. On the other hand, parahilar peribronchial opacification, diffuse interstitial lesion, and normal findings prevailed in the control group. Conclusion : KD patients can have concurrent infections, especially pulmonary symptoms. The cause of KD is likely to be associated with M. pneumoniae infection. Thus, immediate treatment of M. pneumoniae infection in KD patients is very important.
Keywords: Kawasaki disease | Mycoplasma pneumoniae | Radiography | Child
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Supplementary Material  Supplementary Material
Meta-analysis of factors predicting resistance to intravenous immunoglobulin treatment in patients with Kawasaki disease  2016 February;59(2)
Hepatitis associated with Mycoplasma pneumoniae infection in Korean children: a prospective study  2015 June;58(6)
Update of genetic susceptibility in patients with Kawasaki disease  2015 March;58(3)
Mycoplasma pneumoniae associated stroke in a 3-year-old girl  2013 September;56(9)
Sensorineural hearing loss in patients with Kawasaki disease  2015 November;58(11)
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