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Korean J Pediatr 2011 April;54(4) :169-175.
Selective embolization of the internal iliac arteries for the treatment of intractable hemorrhage in children with malignancies
Sul Hee Bae (Bae SH)1, Dong Kyun Han (Han DK)1, Hee Jo Baek (Baek HJ)1, Sun Ju Park (Park SJ)1, Nam Kyu Chang (Chang NK)2, Hoon Kook (Kook H)1, Tai Ju Hwang (Hwang TJ)1
1Departments of Pediatrics, Chonnam National University Medical School, Gwangju, Korea
2Departments of Pediatrics??, Chonnam National University Medical School, Gwangju, Korea
Corresponding Author: Hoon Kook ,Tel: +82.61-379-7696, Fax: +82.61-379-7697, Email:
Copyright © 2011 by The Korean Pediatric Society
Purpose : Acute internal hemorrhage is an occasionally life-threatening complication in pediatric cancer patients. Many therapeutic approaches have been used to control bleeding with various degrees of success. In this study, we evaluated the efficacy of selective internal iliac artery embolization for controlling acute intractable bleeding in children with malignancies. Methods : We retrospectively evaluated the cases of 6 children with various malignancies (acute lymphoblastic leukemia, acute myelogenous leukemia, chronic myelogenous leukemia, T-cell prolymphocytic leukemia, Langerhans cell histiocytosis, and rhabdomyosarcoma), who had undergone selective arterial embolization (SAE) of the internal iliac artery at the Chonnam National University Hwasun Hospital between January 2004 and December 2009. SAE was performed by an interventional radiologist using GelfoamⓇ and/or TornadoⓇ coils. Results : The patients were 5 boys and 1 girl with median age of 6.9 years (range, 0.7–14.8 years) at the time of SAE. SAE was performed once in 4 patients and twice in 2, and the procedure was unilateral in 2 and bilateral in 4. The causes of hemorrhage were as follows: hemorrhagic cystitis (HC) in 3 patients, procedure-related internal iliac artery injuries in 2 patients, and tumor rupture in 1 patient. Initial attempt at conservative management was unsuccessful. Of the 6 patients, 5 (83.3%) showed improvement after SAE without complications. Conclusion : SAE may be a safe and effective procedure for controlling acute intractable hemorrhage in pediatric malignancy patients. This procedure may obviate the need for surgery, which carries an attendant risk of morbidity and mortality in cancer patients with critical conditions.
Keywords: Therapeutic embolization | Pediatric patient | Neoplasms
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