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CASE REPORT
Korean J Pediatr 2011 September;54(9) :385-388.
doi:https://doi.org/10.3345/kjp.2011.54.9.385
Candida tropicalis arthritis of the elbow in a patient with Ewings sarcoma that successfully responded to itraconazole
Seung Youn Kim (Kim SY), Jung Sub Lim (Lim JS), Dong Hwan Kim (Kim DH), Hyeon Jeong Lee (Lee HJ), Joon Bum Cho (Cho JB), Jn Ah Lee (Lee JA), Dong Ho Kim (Kim DH)
Department of Pediatrics, Korean Cancer Center Hospital, Seoul, Korea
Corresponding Author: Dong Ho Kim ,Tel: +82-2-970-2894, Fax: +82-2-970-1970, Email: hearing7@paran.com
Copyright © 2011 by The Korean Pediatric Society
ABSTRACT
Fungal infections are rarely responsible for arthritis. Few cases of fungal arthritis have been reported, even in immunocompromised hosts susceptible to low-virulence organisms. Herein, the authors report the first case of Candida tropicalis arthritis in a child with a solid tumor. A 13-year-old boy with Ewings sarcoma developed arthritis in his elbow during the neutropenic period after chemotherapy. Despite treatment with broad-spectrum antibiotics, his condition did not improve and serial blood cultures failed to reveal any causative organisms. After surgical drainage, culture of the joint fluid revealed the presence of C. tropicalis . Itraconazole treatment was started and after 3 months of therapy, the patient completely recovered full elbow function.
Keywords: Candida tropicalis | Arthritis | Sarcoma | Itraconazole | Neutropenia | Child
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